The Development Cycle at Avesthagen

Avesthagen specializes in the discovery, development and marketing of quality ingredients aimed at degenerative conditions that combine nature, tradition and technology.

In addition to a well-defined development cycle, Avesthagen also offers the following technology advantages as part of its "Natural Products" platform:

ADePt™
ADePt™ is a proprietary Indian medicinal plant resource developed by Avesthagen that contains 3 complimentary data streams:

• Over 3000 formulations described in traditional medicine compendia like Ayurveda, Unani or Siddha compendia classified by disease states. The formulations consist primarily of one or more herbs. They have been developed empirically over several thousand years, and there is demonstrated evidence that several of them have passed extensive pre-clinical and clinical validation. This is primary source for lead selection.

• Listing of more than 2500 medicinal plants, and extensive information about their ethno botanical uses, and pharmacognosy related information. This is used for adding validity to selected leads.

• Listing of the structure of molecules and profiles of more than 15,000 compounds common to plants reported to have biological activity across disease states. It is combined with a proprietary molecular profiling technology called MetaGridTM. It also contains additional biological and chemical analysis of the potential leads.

MetaGrid™
MetaGrid™ is a proprietary comparative metabolite analysis tool for fingerprinting of phytoextracts. It enables us to track up to 250 metabolites across different varieties, batches and extracts of a particular botanical. The result is better reproducibility of extracts and a more exacting tool for quality control at the manufacturing level than is currently available.